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Technological Advantages

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* CAMouse® is the only transgenic antibody discovery platform, which generates full human IgG antibodies in vivo with WT B-cell development and native immune responses.

* CAMouse® employs the natural power of mouse IgH enhancer and IgM with human F(ab') 2 to fulfil WT BCR signalling, to support normal B cell development and to generate a robust immune response.

*Human immunoglobulin transgenes undergo normal V(D)J rearrangement, somatic hyper-mutation and class switching in vivo.

*Therapeutic Antibodies discovered from CAMouse® are fully Human IgG produced directly In Vivo, which are advantageous to antibody expression and manufacture.

Marketing Benefits

Full human transgenic animals are the most productive and druggable platforms to mine therapeutic antibody, CAMouse® has been successfully applied to many therapeutic antibody discovery projects in China, South Korea, the United States.

Independent IP

CAMouse® is one of the transgenic mice platform with independent intellectual property rights in China, Europe and the United States. CAMAB's antibody discovery platform based on human antibody transgenic mice, provides guarantee of innovation for the development of human antibody drugs with independent intellectual.
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